Ep 83 | What You Need to Know Before Going on GLP-1s for Weight Loss


You've probably seen celebrities and influencers losing dramatic amounts of weight on Ozempic and other GLP-1 medications. Maybe you've even considered trying them yourself. Several of my clients and their family members are currently using GLP-1s, and I'll be honest with you—these medications can be incredibly effective for weight loss.

But here's what concerns me as a coach: I'm seeing too many people make the same critical mistakes that set them up to regain all the weight they lost, and sometimes even more. If you're thinking about going on a GLP-1 but you don't plan on changing anything else about your lifestyle, you need to hear this.

I'm Not Against GLP-1s (But There's a Catch)

Let me start by saying I'm not opposed to people using GLP-1 medications to reach their fat loss goals. As someone who's been training clients for over 10 years, I know that fat loss isn't a moral failing or just a matter of willpower. Decades of research have shown us that metabolism, fat storage, hormones, and thyroid function all play complex roles in your ability to lose weight and maintain a healthy body weight.

The key word here is "tool." GLP-1s are one tool in your toolbox—not a magic solution that works in isolation. And if you use this tool without addressing your eating habits, building muscle through resistance training, and changing your movement patterns, you're setting yourself up for disappointment.

How GLP-1 Medications Actually Work

GLP-1 medications like Ozempic, Wegovy, Mounjaro, and Zepbound mimic a natural hormone your body already produces called glucagon-like peptide-1. This hormone regulates blood sugar and appetite. When you take a GLP-1 medication, you're essentially increasing the amount of this hormone in your body, which creates several effects.

First, these medications significantly reduce your appetite and what we call "food noise"—that constant preoccupation with food and cravings. You're just less interested in eating. Second, they slow down gastric emptying, which means food stays in your stomach longer. You feel fuller for longer periods, you don't need to eat as much, and you have longer stretches between meals where you feel satisfied.

For people who struggle with intense cravings, emotional eating, or constant thoughts about food, this can be genuinely life-changing. It can help break the cycle of compulsive eating and give you space to work on your relationship with food.

The Problem Everyone's Ignoring

Here's where most people go wrong: they think the medication alone will solve everything. They lose weight rapidly while on the drug, but they're not exercising, not building muscle, not addressing their eating behaviors or their relationship with food. Then when they go off the medication—and most people don't plan to stay on it forever—their appetite comes roaring back, and so do all their old habits.

The result? They rapidly regain all the weight they lost, and sometimes gain even more. Sound familiar? It's the same pattern I see with fad diets—that frustrating yo-yo cycle of losing and regaining weight.

But there's an even bigger problem. When you lose weight on a GLP-1 without doing resistance training or eating enough protein, you lose significant muscle mass along with the fat. Since muscle is one of the main drivers of your metabolism, losing muscle means your body burns fewer calories each day. So when you go off the medication and start eating normally again, your slower metabolism makes it even easier to regain weight—and harder to lose it again.

What We Don't Know About Long-Term Use

We have solid research on using these medications long-term for type 2 diabetes management. But when it comes to using them specifically for fat loss and their long-term effects on metabolism? The research is limited. If you're planning to stay on these drugs for years, you're essentially signing up to be a guinea pig. That doesn't mean it's necessarily dangerous, but it's a reality you should consider.

The Right Way to Use GLP-1 Medications

If you decide to go on a GLP-1 after talking with your doctor, here's what you absolutely need to do at the same time: use the appetite suppression as an opportunity to build sustainable healthy habits.

While you're not constantly thinking about food and your cravings are reduced, that's your window to change your relationship with food. Work with a coach, therapist, dietitian, or your doctor to develop healthy eating patterns. Learn what appropriate portions look like. Understand how to fuel your body properly. Address any emotional or psychological issues you have with food.

At the same time, get into a consistent exercise routine that prioritizes resistance training. This is crucial for maintaining your muscle mass while you lose weight. The more muscle you preserve or even build while on the medication, the better your metabolism will function when you eventually go off it.

A responsible doctor will encourage both of these things. If your doctor is just handing you a prescription without talking about exercise and nutrition, that's a red flag.

I Understand the Frustration

I want to take a moment to acknowledge how you might be feeling if you're considering GLP-1s. Maybe you've tried multiple diets and exercise programs with limited success. Maybe you have an on-again, off-again relationship with the gym or healthy eating. It's incredibly frustrating, and I get why a medication that promises rapid weight loss sounds appealing.

But I want to caution you against magical thinking. This isn't going to fix the underlying patterns that led to weight gain in the first place. It can, however, make it easier to establish new patterns because you won't be fighting against constant hunger and food preoccupation.

For many of my clients who struggle with using food as their primary way to regulate their nervous system—often tied to childhood trauma or stressful life events—the appetite suppression can be a game-changer. When food doesn't provide the same comfort it used to, it becomes easier to break those habits and develop healthier coping mechanisms. But only if you're actively working on building those new habits while the medication gives you that breathing room.

My Recommendation: Try Other Tools First

Before you commit to a GLP-1, I'd encourage you to honestly assess what you've tried first. Have you actually stuck to a consistent resistance training program? Have you worked with a coach or followed a structured nutrition plan? Have you given sustainable methods a real chance?

If you haven't exhausted those options yet, start there. You might find that with proper guidance on training and nutrition, you can reach your goals without medication. And if you do still decide a GLP-1 is right for you, you'll already have the healthy habits in place that will help you maintain your results.

If you've tried everything and feel stuck, or if you're already on a GLP-1 and want to make sure you're setting yourself up for long-term success, that's exactly what my Fat Loss Transformation program is designed for. I'll teach you how to build sustainable eating habits, how to structure your training to preserve muscle mass, and how to create a healthy relationship with food that lasts beyond any medication.

I also offer resources for every level of support—from DIY options in my Gains Club membership (with downloadable workout plans, recipes, and meal plans) to structured programming on my ABC Trainerize app, to one-on-one coaching for maximum accountability.

The Bottom Line

GLP-1 medications can be an effective tool for weight loss, but they're not a magic bullet. If you use them without also addressing your eating habits, building muscle through resistance training, and working on your relationship with food, you're very likely to regain the weight when you stop the medication.

Use the appetite suppression as an opportunity—a window of time when you can more easily build the sustainable habits that will serve you for life. That's how you achieve lasting fat loss, whether you're on medication or not.

Have questions about GLP-1s or fat loss in general? Drop them in the comments or connect with me on my Twitch channel, in the ABC Trainerize app, or on social media @jaydigains.

 

Subscribe for Updates ✉️

Sign up to get notified whenever new episodes drop. Opt in for more tips on training, fat loss, and nutrition by filling out the form below:

Your privacy is important to me! I will never share your information with any third party. Unsubscribe from the email list at any time.

Fill out the fields below:

* indicates required
I'm interested in emails about
 
Previous
Previous

Ep 84 | How to Navigate the Holidays on a Fitness Journey (Without Losing Your Mind)

Next
Next

Ep 82 | How Hard Should You Train in Heavy Lifting? (Part 3)